Tutorial:Ultimate Guide

How to go from early game to absolute endgame - The Ultimate Guide

 * 1) Leave your island.
 * 2) Buy a Promising Pickaxe, Rookie Hoe and Promising Axe.
 * 3) Get, , skills to level 7.
 * 4) NPC Flip. (Buy Items from NPCs and sell the to the Bazaar.
 * 5) Get some minion slots (Craft more unique minions).
 * 6) Place some Redstone Minions, since the Talisman Bag upgrades are going to be really important.
 * 7) Work on some easy talismans (Buy the ones from the Adventurer)
 * 8) Do the Season of Jerry event (you can get up to by selling Gifts)
 * 9) Now buy a maxed Raider Axe and Ender Armor reforged to Fierce.
 * 10) Get as much Fairy Souls as possible

Mid Game

 * 1) Do some Zealot Grinding. (Unless you can't one shot zealots yet in which case get more talismans or use a talisman optimizer)
 * 2) Get Young Dragon Armor with Farmer Boots or Rancher's Boots. Alternatively, if you are planning to use a God Potion, get a full young set, as the cap will be increased by 100.
 * 3) Sell Summoning Eyes that you obtained from Zealot Grinding
 * 4) A griffin pet works extremely well for stats; the uncommon and above versions grants strength and regeneration effects, both of which are extremely useful
 * 5) Focus on more talismans and minions for some passive money income (at least 70% talisman completion).
 * 6) Use a Minion Spreadsheet to find a minion that consistently makes a good amount of money. Alternatively, continue using collection minions to get more upgrades and recipes.
 * 7) Buy Aspect of the Dragons and an armor set that has a decent damage and EHP boost (Strong Dragon Armor is very commonly used).
 * 8) Start doing Slayer Quests
 * 9) Having all fairy souls is necessity at this point

Now that you have killed some Dragons and gotten level 4 - 5 on all slayers you are:

Late Game
Now this is going to be a lot of money grinding
 * 1) Grind tens of million using any method
 * 2) Get better Pets, such as Blue Whale, Baby Yeti, Sheep, Tiger, and Ender Dragon.
 * 3) Get Frozen Blaze, Superior Dragon or Shadow Assassin armor
 * 4) Do Dungeons (a lot).
 * 5) Get Mana Flux Power Orb or preferably better version.
 * 6) Minimally 90% talisman completion, consider using Recombobulator on at least some of them.
 * 7) Get your Slayer levels higher.
 * 8) Your skill average level should be at least 30 at this point

End Game

 * 1) Max collections one by one
 * 2) Get any of the Wither Armor variants. It might be tempting to get these earlier but it's not worthwhile.
 * 3) Get any of the Necron's Blade variants
 * 4) Get all Slayers to level 8 or 9. Zombie Slayer level 8's perk is actually really good, so it might be worth getting earlier
 * 5) Do any of the methods you have found to get more money on the last few things you are missing
 * 6) Consider grinding skills you have ignored to this point

Absolute End Game

 * 1) Get everything in the game
 * 2) Do everything in the game
 * 3) Grab an Emerald Blade
 * 4) Grab all the pets
 * 5) Max everything out
 * 6) Flex with your millions of damage

Nice, now you know what to do

Final Tips
For more tips, check Tutorials/Tips and Tricks.
 * With every new Dungeon Floor added, the Skill will become easier to level up. Because of this, it is not recommended to grind Dungeons too much and focus on other things too.
 * Most importantly, these are not rules for how to play the game, simply a very efficient means of getting to End Game. The main purpose of video games is having fun, and if building your island or experimenting with overpriced Items is something you enjoy, don't stop yourself from doing it just because others don't. Don't let people bully you because your Skill Average is low or because your networth is 1/2 of theirs, people who take the game too seriously are the last people you should be getting advice from.